Blue Ridge Parkway: With preserved pristine picnic spots, campgrounds and mountain trails, America's longest unspoiled roadway winds from the Shenandoah Valley through North Carolina into the Great Smokies, attracting more than 26 million motorists, hikers and bikers annually and touching Roanoke, the largest city on its path, at Milepost 120.

Peaks of Otter: Milepost 86, Bedford County. Just a short 45-minute drive from Roanoke, this parkway tradition is famous with hikers for its three peaks -- Sharp Top, Flat Top and Hearkening Hill -- as well as other trails that challenge fitness enthusiasts. The lodge is famous for its lavish buffets, the charm of its lake-rimmed facility and the unique, homespun offerings in its gift shop.

Mabry Mill: Milepost 176, Meadows of Dan. The parkway's most-photographed site, this turn-of-the-century grist mill is a favorite spot for tourists and Roanoke Valley motorists in search of delicious food and a quiet one-hour getaway.

Chateau Morrisette Winery: Milepost 171.5, Meadows of Dan. Another favorite parkway stop, guests may tour the winery, indulge in wine tasting, dine at the chateau restaurant, Le Chien Noir, or select from the wide collection of house vintages.